The pharmacology and therapeutic potential of (-)-huperzine A
نویسندگان
چکیده
منابع مشابه
The pharmacology and therapeutic potential of (−)-huperzine A
(-)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer's disease. In this review, we will discuss the pharmacology and therapeutic potential of (-)-huperzine A (1). Synthetic studies of (-)-huperzine A (1) aimed at enabling its...
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Alzheimer's disease (AD) is the fourth leading cause of death in adults, characterized by hallmark neuritic plaques and neurofibrillary tangles. Current treatments focus only on symptom relief. As a possible new treatment option for AD, huperzine A's chemistry, pharmacology, and clinical effectiveness are assessed. The chemical synthesis of huperzine A has been optimized, while an in vitro tech...
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ژورنال
عنوان ژورنال: Journal of Experimental Pharmacology
سال: 2012
ISSN: 1179-1454
DOI: 10.2147/jep.s27084